South African-born, Stanford MBA. Former CFO of PayPal (PayPal Mafia). Joined Sequoia Capital 2003. Led investments in YouTube, Instagram, Square/Block. Became Managing Partner/Steward. Stepped down Nov 2025 (surprise vote), succeeded by Alfred Lin and Pat Grady. Key AI investments: OpenAI, Anthropic (both eyeing 2026 IPOs), Physical Intelligence (robot foundation models), Flow Engineering. Raised $7B expansion fund April 2026. For hardware founders: Sequoia under Botha bet early on Physical Intelligence and 'physical AI' — the thesis that AI will move from screens to the real world.